Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 77 | 05p77-3 | Germany | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 22 |
| 2 | 3TC+AZT | 130 |
| 3 | 3TC+D4T+SQV | 9 |
| 4 | 3TC+D4T+IDV | 31 |
| 5 | D4T+IDV | 8 |
| 6 | DDI+NFV | 9 |
| 7 | DDI+NFV+SQV | 13 |
| 8 | DDI+NVP+RTV+SQV | 43 |
| 9 | DDI+RTV+SQV | 2 |
| 10 | 3TC+ABC+AZT | 2 |
| 11 | 3TC+ABC+AZT+EFV | 92 |
| 12 | APV+DDI+LPV+NVP | 180 |
| 13 | APV+DDI+LPV | 69 |
| 14 | DDI+FPV+LPV | 4 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, V75M, M184MV, L210W, T215Y | K103N, Y181C, G190A | K43E, E44D, K101KR, V118I, D121H, K122DN, D123E, R172RK, D177E, V189I, T200A, Q207D, H208F, R211K, E224EK, D237E, Q278E, T286A, E297R |
| >05p77-3| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKVMDFRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDVGDAYFSIPL HNEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPEIVI CQYVDDLYIASDLEIGQHRAKIEELRDFLWKWGFYTPDKKHQKKPPFLWMGYELHPEKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGAKALTEVIPLTREAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IL, I84V, L90M | L10F, L33F, G73S | L5F, I13IM, G16A, L24F, E34Q, R41K, F53Y, I62V, L63P, I64IM, A71L, I72K, V77I, I93L |
| >05p77-3| codons 1-99 PQITFWQRPFVTMKIAGQLKEALFDTGADDTVFQEMNLPGKWKPKIIGGIGGYLKVRQYD QVPMEICGHKLKSTVLIGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |