Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 77 | 02p77-1 | Germany | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 22 |
| 2 | 3TC+AZT | 130 |
| 3 | 3TC+D4T+SQV | 9 |
| 4 | 3TC+D4T+IDV | 31 |
| 5 | D4T+IDV | 8 |
| 6 | DDI+NFV | 9 |
| 7 | DDI+NFV+SQV | 13 |
| 8 | DDI+NVP+RTV+SQV | 43 |
| 9 | DDI+RTV+SQV | 2 |
| 10 | 3TC+ABC+AZT | 2 |
| 11 | 3TC+ABC+AZT+EFV | 92 |
| 12 | APV+DDI+LPV+NVP | 115 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30DN, M46MI, I84V, L90M | L33LF | L5LF, L10LI, L24LF, R41K, F53Y, I62IV, L63P, A71AV, I72IK, V77I, I93L |
| >02p77-1| codons 1-99 PQITFWQRPIVTIKIGGQLKEALFDTGADNTVFEEMNLPGKWKPKIIGGIGGYIKVRQYD QVPIEICGHKVKGTVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, V75VM, M184V, L210W, T215Y | K103N, G190GA | K43E, E44D, V118VI, D123E, I135IV, D177E, V189VI, T200A, Q207DH, H208F, R211K, E224EK, D237DE, Q278E, T286A, E297R |
| >02p77-1| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKVMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYIASDLEIGQHRAKIEELRHFLWKWGFYTPDKKHQKKPPFLWMGYELHPEKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGAKALTEVIPLTREAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |