Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 70 | 00p70-1 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 313 |
| 2 | 3TC+AZT+D4T | 22 |
| 3 | 3TC+D4T+NFV | 30 |
| 4 | D4T+DDI+NVP | 52 |
| 5 | D4T+DDI+NFV | 109 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | K101EQ, Y181C, G190A | V35I, K43Q, E44D, K49R, K122E, S162D, E169D, D177E, V179I, G196E, Q207N, R211K, A272P, K277R, T286A, E297K |
| >00p70-1| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEQDGKISRIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILDPFRKQNPEIII CQYMDDLYVASDLEIEQHRTKIEELRNHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10F, K43T | L19LI, D60DE, L63P, A71V, I72V, V77I, Q92QK, I93L |
| >00p70-1| codons 1-99 PQITLWQRPFVTIKIGGQIKEALLDTGADDTVLEEMNLPGRWTPKMIGGIGGFVKVRQYE QIPIEICGHKVVGTVLIGPTPANIIGRNLMTKLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |