Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 65 | 02p65-5 | Germany | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 18 |
| 2 | AZT+DDI | 7 |
| 3 | None | 3 |
| 4 | AZT+DDI | 4 |
| 5 | None | 21 |
| 6 | 3TC | 12 |
| 7 | 3TC+AZT | 6 |
| 8 | 3TC+AZT+RTV | 58 |
| 9 | 3TC+AZT+RTV+SQV | 44 |
| 10 | D4T+DDI+RTV+SQV | 75 |
| 11 | D4T+DDI+NFV | 28 |
| 12 | AZT+DDI+IDV+RTV | 10 |
| 13 | 3TC+ABC+D4T+EFV | 22 |
| 14 | ABC+AZT+DDI+LPV | 15 |
| 15 | ABC+DDI+LPV | 1 |
| 16 | ABC+D4T+DDI+LPV | 17 |
| 17 | ABC+APV+DDI+EFV+RTV | 43 |
| 18 | 3TC+ABC+APV+DDI+LPV+RTV+TDF | 11 |
| 19 | None | 3 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54T, V82A, L90M | L10F, L33F, G73T, L89V | G16A, N37D, R41K, I62V, L63P, C67Y, A71V, I72IT, V77I |
| >02p65-5| codons 1-99 PQITLWQRPFVTIKIAGQLKEALLDTGADDTVFEEMDLPGKWKPKIIGGIGGFTKVRQYD QVPIEIYGHKVTTTVLIGPTPANIIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, V75T, M184V, L210W, T215Y | K219E | K103N | A98G, V108I | K20R, V35I, K43Q, V118I, K122V, D123N, I135L, S162D, I178L, I202V, D218E, F227FY, A272P, Q334K |
| >02p65-5| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEQEGKISKIGPENPYNTPV FAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTILDVGDAYFSIPL DVNFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDLVI YQYVDDLYVGSDLEIGQHRTKVEELRQHLWRWGFYTPEEKHQKEPPYLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGK |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |