<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
65 01p65-3 Germany 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 18
2 AZT+DDI 7
3 None 3
4 AZT+DDI 4
5 None 21
6 3TC 12
7 3TC+AZT 6
8 3TC+AZT+RTV 58
9 3TC+AZT+RTV+SQV 44
10 D4T+DDI+RTV+SQV 75
11 D4T+DDI+NFV 28
12 AZT+DDI+IDV+RTV 10
13 3TC+ABC+D4T+EFV 22
14 ABC+AZT+DDI+LPV 15
15 ABC+DDI+LPV 1
16 ABC+D4T+DDI+LPV 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54A, V82A, L90M L33F, G73T L10I, G16A, N37D, R41K, I62V, L63P, A71V, V77I  
>01p65-3| codons 1-99
PQITLWQRPIVTIKIAGQLKEALLDTGADDTVFEEMDLPGKWKPKIIGGIGGFAKVRQYD
QVPIEICGHKVITTVLIGPTPANIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, L210W, T215Y A62AV, V75T, K219Q   A98G V35I, K43Q, V118I, K122V, D123N, S162D, I178L, I202V, D218E, A272P  
>01p65-3| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEQEGKISKIGPENPYNTPV
FVIKKKNSTRWRKITDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSIPL
DVNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDLVI
YQYMDDLYVGSDLEIGQHRTKVEELRQHLWRWGFYTPEQKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKD

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008