Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 65 | 00p65-2 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 18 |
| 2 | AZT+DDI | 7 |
| 3 | None | 3 |
| 4 | AZT+DDI | 4 |
| 5 | None | 21 |
| 6 | 3TC | 12 |
| 7 | 3TC+AZT | 6 |
| 8 | 3TC+AZT+RTV | 58 |
| 9 | 3TC+AZT+RTV+SQV | 44 |
| 10 | D4T+DDI+RTV+SQV | 75 |
| 11 | D4T+DDI+NFV | 28 |
| 12 | AZT+DDI+IDV+RTV | 10 |
| 13 | 3TC+ABC+D4T+EFV | 19 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, V75T, M184V, L210W, T215Y | A62AV, K219Q | L100LI, K103N | A98G, V108VI | V35I, I37F, K43Q, V118I, K122V, D123N, S162D, I178L, I202V, D218E, A272P |
| >00p65-2| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEFCTELEQEGKISKIGPENPYNTPV FVIKKKNSTRWRKITDFRELNKRTQDFWEVQLGIPHPGGIKKNKSVTILDVGDAYFSIPL DVNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDLVI YQYVDDLYVGSDLEIGQHRTKVEELRQHLWRWGFYTPEQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | K43KT, G73ST | L10I, N37D, R41K, L63P, A71V, I72IR, V77I |
| >00p65-2| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMDLPGKWTPKLIGGIGGFVKVRQYD QIPIEICGHKVRTTVLIGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |