<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
61 01p61-4 Germany 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 56
2 AZT+DDC 109
3 3TC+AZT 29
4 3TC+AZT+SQV 54
5 3TC+AZT+IDV 16
6 D4T+NFV 35
7 3TC+AZT+DLV 9
8 3TC+AZT+DLV 8
9 3TC+AZT+RTV 68
10 AZT+DDI+RTV+SQV 50
11 3TC+D4T+LPV 49

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V, L90M   L10I, K20R, E35D, M36I, N37T, R41K, L63P, I66V, A71V, Q92QR, I93L, C95F  
>01p61-4| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDITLPGKWKPKIIGGIGGFVKVRQYD
QIPIEVCGHKVIGTVLVGPTPTNVIGRNLMTRLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, T215Y   K103N   T39A, E44D, V118VI, D123E, E138Q, I142V, D177E, I178L, Q207E, L210S, I293V, P294Q, E297K K43EG
>01p61-4| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEGDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNQTPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPELVI
YQYVDDLYVGSDLEIGQHRTKIEELREHLSRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVQLTKEAE
LELAENREILKEPVHGVYYDPSKD

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008