<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
61 00p61-3 Germany 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 56
2 AZT+DDC 109
3 3TC+AZT 29
4 3TC+AZT+SQV 54
5 3TC+AZT+IDV 16
6 D4T+NFV 35
7 3TC+AZT+DLV 9
8 3TC+AZT+DLV 8
9 3TC+AZT+RTV 68
10 AZT+DDI+RTV+SQV 50
11 3TC+D4T+LPV 23

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V, L90M   L10I, K20R, E35D, M36I, N37T, R41K, L63P, I66V, A71V, I93L, C95F  
>00p61-3| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDITLPGKWKPKIIGGIGGFVKVRQYD
QIPIEVCGHKVIGTVLVGPTPTNVIGRNLMTQLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, T215Y   K103N   T39A, K43E, E44D, V118I, D123E, E138Q, I142V, P170PT, D177E, I178L, E203ED, Q207E, L210S, I293V, P294Q, E297K C280CY
>00p61-3| codons 1-320
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEEDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNQTPGVRYQYNVLPQGWKGSPAIFQSSMTKILETFRKQNPELVI
YQYVDDLYVGSDLEIGQHRTKIDELREHLSRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLYKLLRGTKALTEVVQLTKEAE
LELAENREILKEPVHGVYYD

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008