Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 61 | 00p61-3 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 56 |
| 2 | AZT+DDC | 109 |
| 3 | 3TC+AZT | 29 |
| 4 | 3TC+AZT+SQV | 54 |
| 5 | 3TC+AZT+IDV | 16 |
| 6 | D4T+NFV | 35 |
| 7 | 3TC+AZT+DLV | 9 |
| 8 | 3TC+AZT+DLV | 8 |
| 9 | 3TC+AZT+RTV | 68 |
| 10 | AZT+DDI+RTV+SQV | 50 |
| 11 | 3TC+D4T+LPV | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, I84V, L90M | L10I, K20R, E35D, M36I, N37T, R41K, L63P, I66V, A71V, I93L, C95F |
| >00p61-3| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDITLPGKWKPKIIGGIGGFVKVRQYD QIPIEVCGHKVIGTVLVGPTPTNVIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | K103N | T39A, K43E, E44D, V118I, D123E, E138Q, I142V, P170PT, D177E, I178L, E203ED, Q207E, L210S, I293V, P294Q, E297K | C280CY |
| >00p61-3| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSINNQTPGVRYQYNVLPQGWKGSPAIFQSSMTKILETFRKQNPELVI YQYVDDLYVGSDLEIGQHRTKIDELREHLSRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLYKLLRGTKALTEVVQLTKEAE LELAENREILKEPVHGVYYD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |