<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
60 04p60-5 Germany 2004 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC 52
2 3TC+D4T 35
3 3TC+D4T+NFV+NVP 24
4 3TC+AZT+DDI+SQV 37
5 ABC+D4T+EFV+IDV 96
6 None 226

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82VF, L90M G73S I62V, L63P, A71V, V77I, I93L  
>04p60-5| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYD
QVPIEICGHKVISTVLIGPTPFNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y K219N Y188L   K11R, T39A, V118VI, K122KE, K173N, E203EK, Q207D, R211K, D218E, L228H, A272P, K277R, L283I, R284K, I293V, P294Q, E297A, S322SL  
>04p60-5| codons 1-335
PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNQNPDIVI
YQYVDDLLVGSDLEIGQHRTKIKELRDHLWKWGFYTPENKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIKGTKALTEVVQLTAEAE
LELAENREILKEPVHGVYYDPLKDLIAEIQKQGQG

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008