Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 60 | 04p60-5 | Germany | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC | 52 |
| 2 | 3TC+D4T | 35 |
| 3 | 3TC+D4T+NFV+NVP | 24 |
| 4 | 3TC+AZT+DDI+SQV | 37 |
| 5 | ABC+D4T+EFV+IDV | 96 |
| 6 | None | 226 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82VF, L90M | G73S | I62V, L63P, A71V, V77I, I93L |
| >04p60-5| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYD QVPIEICGHKVISTVLIGPTPFNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K219N | Y188L | K11R, T39A, V118VI, K122KE, K173N, E203EK, Q207D, R211K, D218E, L228H, A272P, K277R, L283I, R284K, I293V, P294Q, E297A, S322SL |
| >04p60-5| codons 1-335 PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNQNPDIVI YQYVDDLLVGSDLEIGQHRTKIKELRDHLWKWGFYTPENKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIKGTKALTEVVQLTAEAE LELAENREILKEPVHGVYYDPLKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |