Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 59 | 01p59-3 | Germany | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 489 |
| 2 | 3TC+AZT+SQV | 29 |
| 3 | D4T+NFV+SQV | 10 |
| 4 | None | 22 |
| 5 | 3TC+D4T | 1 |
| 6 | 3TC+AZT+D4T | 4 |
| 7 | 3TC+AZT+D4T+IDV | 8 |
| 8 | 3TC+AZT+IDV | 27 |
| 9 | 3TC+AZT+IDV | 19 |
| 10 | D4T+DDI+EFV | 34 |
| 11 | D4T | 7 |
| 12 | 3TC+ABC+D4T | 2 |
| 13 | 3TC+ABC+D4T+LPV | 68 |
| 14 | 3TC+ABC+LPV | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | G73S | L10I, K14R, I15V, N37E, L63P, A71V, V77VI |
| >01p59-3| codons 1-99 PQITLWQRPIVTIRVGGQLKEALLDTGADDTVLEEMELPGRWKPKMIGGIGGFVKVRQYD QIPIEICGHKVISTVLIGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K103N | P4PS, T39A, K122E, D123N, I135T, I142V, S162C, V245T, K277R, T286A, A288S, I293V, E297K |
| >01p59-3| codons 1-324 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKSLTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |