Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 54 | 99p54-1 | France | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 230 |
| 2 | 3TC+D4T+SQV | 9 |
| 3 | 3TC+D4T+NFV | 35 |
| 4 | DDI+IDV+RTV | 31 |
| 5 | DDI+IDV+NVP+RTV | 38 |
| 6 | 3TC+ABC+EFV | 15 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K219KE | Y181C, G190S | V8I, K43E, K101Q, V118I, K122E, V179I, I202V, E203K, Q207E, A272P, Q278QH, T286A | E40E* |
| >99p54-1| codons 1-324 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALVEICT*LEEEGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII CQYVDDLYVSSDLEIGQHRTKVKELREHLWRWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, N37S, L63P |
| >99p54-1| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDMSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |