Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 50 | 00p50-1 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 2 |
| 2 | None | 115 |
| 3 | 3TC+AZT | 17 |
| 4 | 3TC+AZT+SQV | 9 |
| 5 | 3TC+AZT+RTV | 6 |
| 6 | 3TC+AZT | 2 |
| 7 | 3TC+AZT+SQV | 10 |
| 8 | D4T+IDV | 19 |
| 9 | None | 9 |
| 10 | D4T+DDI+IDV | 1 |
| 11 | D4T+IDV | 3 |
| 12 | None | 22 |
| 13 | ABC+D4T+IDV+RTV | 5 |
| 14 | D4T+DDI+NFV | 102 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | T39A, S68G, V90I, V106I, I135T, T165I, Q174QR, R211G, H221Y, A272P, K277R, L283I, I293V, P294Q, I309L |
| >00p50-1| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSITVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKRNPDIVI CQYMDDLYVGSDLEIGQHRTKIEELRQHLLGWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVVQLTEEAE LELAENRELLKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, I62V, L63P, V77I, I93L |
| >00p50-1| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |