Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48 | 00p48-4 | Turkey | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 100 |
| 2 | AZT+DDC | 35 |
| 3 | AZT+DDC+SQV | 35 |
| 4 | 3TC+D4T+NFV | 50 |
| 5 | DDI+IDV+NVP | 45 |
| 6 | ABC+APV+D4T+EFV | 9 |
| 7 | ABC+D4T+EFV | 1 |
| 8 | 3TC+ABC+D4T+EFV | 34 |
| 9 | 3TC | 6 |
| 10 | 3TC+AZT+LPV | 37 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A | K43T | L10I, T12S, I13V, K20I, M36I, L63P, T74S |
| >00p48-4| codons 1-99 PQITLWQRPIVSVKIGGQLIEALLDTGADDTVLEEINLPGRWTPKMIVGIGGFVKVRQYD QIPIEICGHKAIGSVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | Y181C, G190S | P4S, K20R, T27S, V35M, K43E, E44D, A98S, K101Q, V118I, K122E, I135V, K166R, G196E, E203K, Q207E, R211K, V245E, A272S, I293V, E312Q |
| >00p48-4| codons 1-324 PISSIETVPVKLKPGMDGPRVKQWPLSEEKIKALMEICTELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLQKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI CQYVDDLYVSSDLEIEQHRTKIKELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKQPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |