Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 39 | 08p39-3 | Zaire | 2008 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 148 |
| 2 | AZT+DDI | 3 |
| 3 | 3TC+AZT+DDI | 1 |
| 4 | 3TC+AZT | 19 |
| 5 | 3TC+AZT+NVP | 29 |
| 6 | 3TC+AZT+RTV | 3 |
| 7 | 3TC+AZT+IDV | 6 |
| 8 | 3TC+IDV | 48 |
| 9 | None | 4 |
| 10 | 3TC+AZT+IDV | 27 |
| 11 | D4T+DDI | 1 |
| 12 | D4T+DDI+EFV | 2 |
| 13 | D4T+EFV | 1 |
| 14 | ABC+D4T+EFV | 101 |
| 15 | 3TC+AZT+DDI+LPV | 181 |
| 16 | 3TC+ATV+AZT+DDI+RTV | 174 |
| 17 | ATV+FTC+RTV+TDF | 40 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74V, M184V | T215V, K219Q | Y188L | K11T, V35T, T39N, D121H, K122E, A158S, K173S, Q174K, D177E, G196E, Q207A, V245Q, A272G, T286A, E291D, I293V, K311R, E312D |
| >08p39-3| codons 1-334 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRSKNPEIVI YQYVDDLLVGSDLEIEQHRTKIEELRAHLLRWGFVTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYGGIKVKQLCKLLRGAKALTDVVPLTEEAE LELAENREILRDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, M36I, R41K, K45R, L63P, H69K, A71T, L89M |
| >08p39-3| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKTIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |