Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 39 | 01p39-1 | Zaire | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 148 |
| 2 | AZT+DDI | 3 |
| 3 | 3TC+AZT+DDI | 1 |
| 4 | 3TC+AZT | 19 |
| 5 | 3TC+AZT+NVP | 29 |
| 6 | 3TC+AZT+RTV | 3 |
| 7 | 3TC+AZT+IDV | 6 |
| 8 | 3TC+IDV | 48 |
| 9 | None | 4 |
| 10 | 3TC+AZT+IDV | 27 |
| 11 | D4T+DDI | 1 |
| 12 | D4T+DDI+EFV | 2 |
| 13 | D4T+EFV | 1 |
| 14 | ABC+D4T+EFV | 101 |
| 15 | 3TC+AZT+DDI+LPV | 54 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, K45R, L63LP, H69K, L89M |
| >01p39-1| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, V35T, T39N, K49KR, V60I, T69S, D121HY, K122E, A158S, T165TI, K173S, Q174K, D177E, G196E, Q207A, V245Q, A272AG, K281KR, T286A, E291D, I293V, E297EK, K311KR, E312D, D324DE |
| >01p39-1| codons 1-324 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISRIGPENPYNTPI FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMIKILEPFRSKNPEIVI YQYMDDLYVGSDLEIEQHRTKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYGGIKVKQLCRLLRGAKALTDVVPLTKEAE LELAENREILRDPVHGVYYDPSKE |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |