Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 38 | 99p38-1 | Germany | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 48 |
| 2 | AZT+DDI | 91 |
| 3 | 3TC+AZT | 13 |
| 4 | 3TC+AZT+SQV | 39 |
| 5 | 3TC+AZT+IDV | 4 |
| 6 | 3TC+AZT | 13 |
| 7 | 3TC+D4T+NFV | 35 |
| 8 | D4T+RTV+SQV | 8 |
| 9 | ABC+RTV+SQV | 4 |
| 10 | 3TC+ABC+NVP | 8 |
| 11 | 3TC+ABC+IDV+NVP | 5 |
| 12 | None | 9 |
| 13 | 3TC+ABC+EFV | 57 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M, M184V | A62V, D67DG, V75I, F77L, F116Y, K219Q | K103N, Y181C, G190A | E6EK, T69N, K101KR, K122E, D177E, T200A, I202V, Q207E, F214FL, L228H, A272P |
| >99p38-1| codons 1-324 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKGSNKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDVGDAFYSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYVDDLYVASDLEIGQHRAKVEELREHLLRWGLTTPDQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | I13V, K20I, M36I, I62V, L63P, I64V, T74S |
| >99p38-1| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QVPVEICGHKAIGSVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |