Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 37 | 04p37-1 | Italy | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 46 |
| 2 | 3TC+AZT | 9 |
| 3 | 3TC+AZT+SQV | 22 |
| 4 | 3TC+D4T+SQV | 70 |
| 5 | 3TC+D4T+IDV | 26 |
| 6 | 3TC+D4T+IDV+NVP | 39 |
| 7 | DDI+NFV+NVP | 1 |
| 8 | ABC+DDI+NFV+NVP | 1 |
| 9 | None | 3 |
| 10 | APV+DDI+NFV+NVP | 26 |
| 11 | D4T+DDI+NVP | 22 |
| 12 | D4T+DDI | 4 |
| 13 | D4T+DDI+LPV | 193 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | K219N | Y181C | T39A, K49R, V118I, K122E, V179I, H208Y, R211K, F214L, L228H, V245K, I293V, P313S |
| >04p37-1| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISRIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII CQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGLYTPDNKHQKEPPFHWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKESVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82S, I84V | L10I, E34Q, L63P, A71T |
| >04p37-1| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLQEMNLPGRWKPKMIVGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPSNVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |