Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1276 | CA13955 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 60 |
| 2 | DDC | 25 |
| 3 | 3TC+AZT | 104 |
| 4 | 3TC+AZT+SQV | 74 |
| 5 | 3TC+AZT | 49 |
| 6 | None | 11 |
| 7 | D4T+DDI+EFV | 19 |
| 8 | ABC+D4T+EFV | 26 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, L63H, I64V |
| >CA13955| codons 1-99 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIHVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20KR, T69TP, K122E, D123E, R125RG, I135T, I178M, G196E, T200A | T131TA, Y144YN, D218DY |
| >CA13879| codons 1-252 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSPKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFGKYTAFAIPSTNNETPGIRNQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPYKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSW |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |