<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
27 07p27-8 Germany 2007 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 6
2 AZT+DDC 96
3 3TC+AZT+SQV 45
4 3TC+AZT+SQV 217
5 D4T+NVP+TDF 89
6 None 148

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   L10V, I13V, R41K, L63P, T74S, V77I, I93L  
>07p27-8| codons 1-99
PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGHKAIGSVLIGPTPVNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    G190GE   E40EK, K49KR, V60VI, S68G, V90I, K122KE, D123E, I135T, T139TA, S162A, K166KR, Q174AE, D177E, V179I, I195IM, Q207E, R211RK, V292VI, I293V, E297EK E302A
>07p27-8| codons 1-303
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTKMEKEGKISRIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNEAPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRKENPEIII
YQYMDDLYVESDLEMGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEIVPLTKEAE
LAL

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008