Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 27 | 05p27-7 | Germany | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 6 |
| 2 | AZT+DDC | 96 |
| 3 | 3TC+AZT+SQV | 45 |
| 4 | 3TC+AZT+SQV | 217 |
| 5 | D4T+NVP+TDF | 89 |
| 6 | None | 45 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L210LW, T215CNSY | Y188L | K49R, V60VI, S68G, V90I, D123E, I135T, S162D, Q174A, D177E, V179I, Q207E, R211K, R284RK, V292VI, I293V, P294PA, E297K, D324E |
| >05p27-7| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPI FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKANPEIII YQYMDDLLVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKALTEIVALTKEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10IV, I13V, R41K, L63P, T74S, V77I, I93L |
| >05p27-7| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGSVLIGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |