Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 27 | 04p27-4 | Germany | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 6 |
| 2 | AZT+DDC | 96 |
| 3 | 3TC+AZT+SQV | 45 |
| 4 | 3TC+AZT+SQV | 217 |
| 5 | D4T+NVP+TDF | 89 |
| 6 | None | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| S48ST, K49R, V90I, D123E, S134SC, I135IATV, Q174E, D177E, V179I, R199RK, Q207E, R211K, V245VM, V254VI, I293IV, E297K, I326V |
| >04p27-4| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKITRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPCVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKENPEIII YQYMDDLYVGSDLEIGQHKTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTINDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| R41K, I62IV, L63P, V77I, I93L |
| >04p27-4| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |