Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 25 | 00p25-1 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 87 |
| 2 | AZT+DDI | 78 |
| 3 | AZT+DDC | 64 |
| 4 | 3TC+AZT | 102 |
| 5 | 3TC+AZT+NFV | 20 |
| 6 | 3TC+AZT | 4 |
| 7 | 3TC+AZT+D4T | 1 |
| 8 | D4T | 8 |
| 9 | 3TC+D4T+IDV | 120 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, T215Y | D67G | K20R, V60I, S68G, R83K, D123E, I135V, R211K, V245E, A272P, E297K |
| >00p25-1| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKGGDKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L | L10R, K55R, L63P, I93L | D29A |
| >00p25-1| codons 1-99 PQITLWQRPRVTIKIGGQLKEALLDTGAADTVLEEMNLPGRWKPKLIGGIGGFIRVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |