Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5607 | CA13949 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | None | 161 |
| 3 | IDV | 57 |
| 4 | D4T+IDV | 43 |
| 5 | D4T+EFV+NFV | 81 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, I84V, L90M | L89V | L10I, I13V, Q18H, E35D, M36I, N37D, I62V, L63P, A71V, I72K, P79A | A22C |
| >CA13949| codons 1-99 PQITLWQRPIVTVKIGGHLKECLLDTGADDTVLEDIDLPGRWKPKLIGGIGGFVKVRQYD QVPIEICGHKVKGTVLVGATPVNVIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | Y181C | S105SA, E203K, H208Y, R211K, K223E |
| >CA13880| codons 1-259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKAVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRTKIKELRQYLWKWGFYTPDKKHQEEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQK |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |