Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 22 | 01p22-1 | Germany | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 126 |
| 2 | AZT+DDI | 26 |
| 3 | AZT+DDC | 52 |
| 4 | AZT | 122 |
| 5 | AZT+DLV | 13 |
| 6 | 3TC+AZT | 70 |
| 7 | 3TC+AZT+SQV | 112 |
| 8 | D4T+DDI+EFV | 10 |
| 9 | ABC+D4T+EFV | 17 |
| 10 | ABC+D4T+EFV+IDV | 18 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10I, K20I, M36I, R41K, K43R, I62V, L63P, A71V, I72T, T74A, I93L |
| >01p22-1| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD QVPIEICGHKVTGAVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, L210W, T215Y | L100I, K103N | Y318F | K43Q, E44D, R83K, V111I, K122E, I142V, D177G, G196E, E203Q, Q207D, H208Y, R211K, Q278E, I293V, E297K | E29K, N57Y |
| >01p22-1| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEKKIKALVEICTELEQDGKISKIGPENPYYTPV FAIKKKNSDKWRKVVDFRELNKKTQDFWEVQLGIPHPAGIKKNKSVTVLDIGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPGIVI YQYVDDLYVGSDLEIEQHRTKIQELRDYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVFYDPSKD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |