Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 19 | 00p19-1 | Unknown | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 40 |
| 2 | DDI | 104 |
| 3 | AZT+DDI | 27 |
| 4 | DDI | 52 |
| 5 | 3TC+AZT | 31 |
| 6 | 3TC | 19 |
| 7 | 3TC+D4T | 28 |
| 8 | 3TC+D4T+IDV | 35 |
| 9 | 3TC+AZT+SQV | 5 |
| 10 | AZT+DDI+NFV+SQV | 10 |
| 11 | 3TC+D4T+RTV+SQV | 5 |
| 12 | D4T+DDI+IDV+SQV | 15 |
| 13 | D4T+DDI+RTV+SQV | 5 |
| 14 | D4T+DDI | 1 |
| 15 | None | 15 |
| 16 | D4T+DDI+RTV | 5 |
| 17 | D4T+DDI+NVP | 21 |
| 18 | ABC+D4T+DDI+EFV | 3 |
| 19 | D4T+DDI+NVP | 61 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, I15V, G16E, E35D, N37S, R41K, K45KR, L63T, I72T |
| >00p19-1| codons 1-99 PQITLWQRPIVTVRVEGQLKEALLDTGADDTVLEDMSLPGKWKPRMIGGIGGFIKVRQYD QITIEICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74LV, L210W, T215Y | K219R | K103KN, Y181C | V108VI, K238KN | V35I, K43Q, V118I, K122E, I135L, S162C, V179VI, E203D, H208F, R211K, D218E, L228LR, V245K, A272P, A288S, I293V | P25L, T27I |
| >00p19-1| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWLLIEEKIKALIEICTELEQEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSIPL DEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII CQYMDDLYVGSDLEIGQHRTKIDELRQFLWKWGFYTPERKHQKEPPFRWMGYELHPDNWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |