Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 18 | 02p18-1 | Germany | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 30 |
| 2 | AZT+RTV | 22 |
| 3 | AZT+DDI+RTV | 9 |
| 4 | AZT+RTV | 17 |
| 5 | 3TC+AZT+RTV | 22 |
| 6 | 3TC+AZT+IDV | 135 |
| 7 | 3TC+AZT+IDV | 56 |
| 8 | 3TC+AZT+NVP | 13 |
| 9 | 3TC+NVP | 100 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | K103N | Y318F | V60VI, K102Q, I135T, S162A, V245K, E312Q |
| >02p18-1| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKQPVHGVFYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A | N37NH, I64V, V77I |
| >02p18-1| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMHLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |