Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 17 | 01p17-3 | Unknown | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 25 |
| 2 | None | 30 |
| 3 | 3TC+AZT | 4 |
| 4 | AZT+SQV | 52 |
| 5 | AZT+DDC+IDV+SQV | 5 |
| 6 | AZT+SQV | 10 |
| 7 | AZT+NFV+SQV | 11 |
| 8 | AZT+D4T+DDI+NVP+RTV+SQV | 11 |
| 9 | AZT+DDI+NVP+RTV+SQV | 30 |
| 10 | AZT+DDI+NVP+RTV+SQV | 46 |
| 11 | AZT+DDI+NVP+RTV+SQV | 36 |
| 12 | None | 16 |
| 13 | 3TC+APV+D4T | 56 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, L90M | L23I, L33F, F53L, G73S | L10I, I13V, I15V, K20R, L63P, H69R, A71V, V77I |
| >01p17-3| codons 1-99 PQITLWQRPIVTVKVGGQLREAILDTGADDTVFEEMNLPGRWKPKIIGGIGGLMKVRQYD QIPIEICGRKVISTVLIGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, L210W, T215Y | D67S | K103N, Y181C | K20R, V35M, T69S, K122KE, I135M, E138Q, S162A, V179I, R211K, K277R, Q278E, T286A, E297K |
| >01p17-3| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV FAIKKKSSSKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSMNNQTPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIII CQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRELCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |