Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 17 | 00p17-1 | Unknown | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 25 |
| 2 | None | 30 |
| 3 | 3TC+AZT | 4 |
| 4 | AZT+SQV | 52 |
| 5 | AZT+DDC+IDV+SQV | 5 |
| 6 | AZT+SQV | 10 |
| 7 | AZT+NFV+SQV | 11 |
| 8 | AZT+D4T+DDI+NVP+RTV+SQV | 11 |
| 9 | AZT+DDI+NVP+RTV+SQV | 30 |
| 10 | AZT+DDI+NVP+RTV+SQV | 46 |
| 11 | AZT+DDI+NVP+RTV+SQV | 34 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, L74LV, L210W, T215Y | D67GS, F116FY | K103N, Y181C | K20R, T69S, I135M, E138EQ, S162A, V179VI, R211K, K277R, Q278E, T286A, E297K |
| >00p17-1| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKSSSRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DKDFRKYTAFTIPSMNNQTPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIII CQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRELCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L23I, F53L, G73S | L10I, I13V, I15IV, K20KR, I62IV, L63P, H69R, A71V, V77I |
| >00p17-1| codons 1-99 PQITLWQRPIVTVKVGGQLREAILDTGADDTVLEEMNLPGRWKPKIIGGIGGLIKVRQYD QVPIEICGRKVISTVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |