Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 16 | 02p16-1 | Thailand | 2002 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 54 |
| 2 | DDI | 11 |
| 3 | AZT+DDI | 36 |
| 4 | AZT+DDI+NVP | 3 |
| 5 | AZT+NVP | 4 |
| 6 | 3TC+AZT+NVP | 9 |
| 7 | 3TC+AZT | 28 |
| 8 | 3TC+AZT+NVP | 11 |
| 9 | 3TC+D4T+NVP | 4 |
| 10 | 3TC+D4T+SQV | 24 |
| 11 | 3TC+D4T+RTV+SQV | 2 |
| 12 | None | 25 |
| 13 | D4T+DDI+EFV+IDV | 9 |
| 14 | None | 10 |
| 15 | D4T+DDI+IDV | 12 |
| 16 | None | 54 |
| 17 | 3TC+AZT+NVP | 91 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, T12A, I13V, E35D, M36I, R41K, R57K, L63LAPV, H69K, K70KR, L89M |
| >02p16-1| codons 1-99 PQITLWQRPIVAVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIVIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184I, L210W, T215Y | K101E, Y181C, G190A | E6ED, V35T, T39K, K43E, E44A, K122E, D123S, I135T, E138EQ, S162T, K173I, Q174K, D177E, I178M, V179I, T200A, E203D, Q207AD, R211RK, H221Y, V245E, A272P, T286A, V292I, I293V, E312T, I326V, I329V | S3CG |
| >02p16-1| codons 1-334 PIGPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKELEEAGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNQTPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRIKNPEMII CQYIDDLYVASDLEIGQHRAKIDELRDHLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQ |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |