Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 11 | 99p11-1 | Germany | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 122 |
| 2 | AZT+DDI | 113 |
| 3 | AZT | 17 |
| 4 | AZT+DDC | 30 |
| 5 | 3TC+D4T | 4 |
| 6 | 3TC+D4T+IDV | 43 |
| 7 | 3TC+D4T+SQV | 4 |
| 8 | D4T+NFV+SQV | 52 |
| 9 | D4T+NFV | 1 |
| 10 | 3TC+ABC+EFV+NFV | 9 |
| 11 | 3TC+ABC+EFV | 65 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, L74I, Y115F, M184V | D67G, K219Q | K103N, V106A | F227L | T69N, R83K, I202V, K277KR, T286A, E291D | L283LF |
| >99p11-1| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKGSNRWRKIVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSATVLDVGDAFFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKVEELRQHLLRWGFTTPDQKHQKEPPLLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLFRGAKALTDVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, L63P, V77I, I93L |
| >99p11-1| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |