Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 10 | 00p10-2 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 126 |
| 2 | AZT+DDC | 78 |
| 3 | AZT+DDI | 21 |
| 4 | 3TC+AZT | 13 |
| 5 | 3TC+D4T | 39 |
| 6 | 3TC+D4T+IDV | 5 |
| 7 | 3TC+D4T+SQV | 37 |
| 8 | 3TC+D4T+NFV+SQV | 2 |
| 9 | D4T+NFV+SQV | 44 |
| 10 | D4T+NVP+RTV+SQV | 14 |
| 11 | 3TC+AZT+IDV | 31 |
| 12 | ABC+D4T+EFV | 62 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | Y188L | K20R, V35I, K43E, E44D, R83K, K102KQ, V106L, V118I, K122E, I135L, S162Y, T165Q, R211K, K223KT, V245K, A272P, K277R |
| >00p10-2| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKKTQDFWEVQLGIPHPAGLKQKKSLTVLDVGDAYFSIPL DEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQYSMQKILEPFRKQNPDIVI YQYVDDLLVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQTEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | L10LV, I15IV, N37AS, L63HQ, I64V, V77I |
| >00p10-2| codons 1-99 PQITLWQRPVVTIKVGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QIQVEICGHKAIGTVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |