Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 6 | 00p6-3 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC | 57 |
| 2 | 3TC+DDC | 57 |
| 3 | 3TC+DDC+IDV | 18 |
| 4 | 3TC+D4T+IDV | 69 |
| 5 | 3TC+ABC+RTV+SQV | 4 |
| 6 | 3TC+NVP+RTV+SQV | 13 |
| 7 | 3TC+DDI+RTV | 4 |
| 8 | 3TC+DDI+EFV+RTV | 22 |
| 9 | 3TC+DDI+EFV+RTV | 2 |
| 10 | DDI+EFV+RTV | 30 |
| 11 | D4T+DDI+EFV+RTV | 34 |
| 12 | 3TC+D4T+DDI+LPV | 27 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | V75A, F77L, F116Y | K103N | P4PS, V35L, T69N, K73M, K101R, K122E, I135V, K173T, T200E, R211K, V245E, K277R, I293V, E297Q, D320DY |
| >00p6-3| codons 1-324 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNKWRMLADLRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDVGDAYYSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTQNPDIVI YQYVDDLYVGSDLEIGQHREKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTQEAE LELAENREILKEPVHGVYYYPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L24I | L10I, I15IV, M36MI, R41K, L63P, A71T, I72V |
| >00p6-3| codons 1-99 PQITLWQRPIVTIKVGGQLKEALIDTGADDTVLEEINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTVGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |