Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 6 | 00p6-2 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC | 57 |
| 2 | 3TC+DDC | 57 |
| 3 | 3TC+DDC+IDV | 18 |
| 4 | 3TC+D4T+IDV | 69 |
| 5 | 3TC+ABC+RTV+SQV | 4 |
| 6 | 3TC+NVP+RTV+SQV | 13 |
| 7 | 3TC+DDI+RTV | 4 |
| 8 | 3TC+DDI+EFV+RTV | 22 |
| 9 | 3TC+DDI+EFV+RTV | 2 |
| 10 | DDI+EFV+RTV | 30 |
| 11 | D4T+DDI+EFV+RTV | 34 |
| 12 | 3TC+D4T+DDI+LPV | 15 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L24I | L10I, I15V, R41K, L63P, A71T, I72V | P81PL |
| >00p6-2| codons 1-99 PQITLWQRPIVTIKVGGQLKEALIDTGADDTVLEEMNLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTVGTVLVGPTLANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | V75A, F77L, F116Y | K103N, V106VA | P225PH | V35L, T69NS, K73M, K101KR, K122E, I135V, K173T, T200E, E203EK, R211K, L228LR, V245E, K277R, I293V, E297Q |
| >00p6-2| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRMLADLRELNKRTQDFWEVQLGIPHPAGLRKNKSATVLDVGDAYYSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTQNPDIVI YQYVDDLYVGSDLEIGQHREKIKELRQHLLKWGFTTPDKKHQKEHPFRWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTQEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |