<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
5 03p5-3 Germany 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 DDC 100
2 AZT+DDC 9
3 3TC+D4T+NFV 281
4 3TC+NFV+TDF 50

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N N88D K20R, E35D, M36I, N37D, R41K, I62V, I64V, V77I  
>03p5-3| codons 1-99
PQITLWQRPLVTIKIGGQLREALLDTGADNTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QVLVEICGHKAIGTVLIGPTPVNIIGRDLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y       K43Q, V60I, K122E, D123S, I135T, T139M, S162Y, K166Q, D250DE, A272P, K277R  
>03p5-3| codons 1-325
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNEMPGIRYQYNVLPQGWKGSPAIFQYSMTQILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDL

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008