Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3961 | CA13939 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 104 |
| 2 | 3TC+ AZT+ IDV | 52 |
| 3 | SQV+ D4T+ RTV | 99 |
| 4 | ABC+ D4T+ DDI+ EFV | 55 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | F53Y, I62V, L63P, V77I, Q92R, I93L, C95F |
| >CA13939| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGYIKVRQYD QVPIEICGHKAIGTVLIGPTPVNVIGRNLMTRLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, L210W, T215Y | K219KR | K103N | K20R, K43N, E44D, V118I, K122E, N175Y, G196E, Q207E, R211K, T286A, I293V, E297K | I270T |
| >CA13873| codons 1-302 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELENDGKISKIGPENPYNTPV FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQYPDIVI YQYMDDLYVGSDLEIEQHRTKIEELREHLWKWGFYTPDRKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQTYAGIKVKQLCKLLRGAKALTEVVPLTKEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |