Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2 | 03p2-6 | Germany | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 26 |
| 2 | AZT+DDI | 9 |
| 3 | 3TC+AZT | 33 |
| 4 | 3TC+AZT+IDV | 11 |
| 5 | AZT+IDV | 13 |
| 6 | D4T+IDV | 8 |
| 7 | AZT+DDI+IDV | 31 |
| 8 | DDI+RTV+SQV | 31 |
| 9 | ABC+D4T+NFV | 2 |
| 10 | ABC+D4T+EFV+NFV | 48 |
| 11 | ABC+EFV+NFV | 22 |
| 12 | None | 26 |
| 13 | APV+DDI+LPV+NVP | 15 |
| 14 | APV+LPV+NVP | 9 |
| 15 | APV+LPV | 2 |
| 16 | 3TC+APV+AZT+LPV | 48 |
| 17 | 3TC+AZT+LPV | 10 |
| 18 | 3TC+IDV+LPV+TDF | 8 |
| 19 | 3TC+IDV+TDF | 28 |
| 20 | None | 4 |
| 21 | 3TC+ABC+AZT | 34 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10F, L33F, F53L | I13V, K20T, R41K, K55R, R57K, I62V, L63P, A71I, I72V, I93L, C95F |
| >03p2-6| codons 1-99 PQITLWQRPFVTVKIGGQLTEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGLVRVKQYD QVPIEICGHKIVGTVLVGPTPANIIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | A98AG | E28EK, T39A, E44D, V118I, K122E, I135T, S162C, Q207E, R211RK, L228H, V245E, L283I, I293V |
| >03p2-6| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALVEICAELEKDGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |