<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2 00p2-3 Germany 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 26
2 AZT+DDI 9
3 3TC+AZT 33
4 3TC+AZT+IDV 11
5 AZT+IDV 13
6 D4T+IDV 8
7 AZT+DDI+IDV 31
8 DDI+RTV+SQV 31
9 ABC+D4T+NFV 2
10 ABC+D4T+EFV+NFV 48
11 ABC+EFV+NFV 22
12 None 26
13 APV+DDI+LPV+NVP 15
14 APV+LPV+NVP 6

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74IV, L210W, T215Y   K101P, K103N   T39A, E44D, A98S, V118I, K122E, I135T, S162C, Q207E, R211RK, L228H, V245E, L283I, I293V  
>00p2-3| codons 1-322
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKDGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLPKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPS

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M L10F, L33F, F53L R41K, K55R, R57K, I62V, L63P, A71I, I72V, I93L, C95F  
>00p2-3| codons 1-99
PQITLWQRPFVTIKIGGQLKEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGLVRVKQYD
QVPIEICGHKIVGTVLVGPTPANIIGRNLMTQLGFTLNF

References
Author Title Citation
Rosen-Zvi, M Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics, 2008