Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1451 | CA13931 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+Unknown | NA |
| 2 | 3TC+D4T+IDV | 47 |
| 3 | D4T+DDI+NFV | 55 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10F, N88D | I15V, K20KT, E35D, M36V, R57K, L63P, I85IV, Q92QR, I93L |
| >CA13931| codons 1-99 PQITLWQRPFVTIKVGGQLTEALLDTGADNTVLEDVNLPGRWKPKMIGGIGGFIKVKQYD QIPIEICGHKAIGTVLVGPTPVNIVGRDLLTRLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | E6D, K11R, K20R, K64R, T69N, R83K, A98S, T200I, Q207D, R211RK, K249R, A272P, K277R, T286A, I293V, E297R | R72RG, K281KN |
| >CA13863| codons 1-303 PISPIDTVPVRLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKDSNRWGKLVDFRELNKKTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRIKIEELRDHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPERDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCNLLRGAKALTEVVPLTREAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |