Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4076 | CA13930 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | NA |
| 2 | NRTI | NA |
| 3 | SQV | 30 |
| 4 | D4T+DDC+IDV | 21 |
| 5 | RTV+SQV | 69 |
| 6 | NFV+SQV | 10 |
| 7 | ABC+DDI+EFV | 8 |
| 8 | D4T+DDI+EFV | 40 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L10I, L63P, A71T, I85V, Q92R | C95M |
| >CA13930| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKTIGTVLVGPTPVNVVGRNLMTRIGMTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103N | V108I | K43E, K122E, G196E, R211K, V245K, E248EK, T286A, I293IL, E297K |
| >CA13878| codons 1-302 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPKKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVLPLTKEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |