Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5608 | CA13916 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L10F | E35D, M36V, N37S, I62V, L63A, I64V, T74S, I93L |
| >CA13916| codons 1-99 PQITLWQRPFVTIKIGGQLKEALLDTGADDTVLEDVSLPGRWKPKMIGGIGGFIKVRQYD QVAVEICGHKAIGSVLVGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | K219N | K103N, Y181YC, Y188C | D121H, K122E, I135T, I142V, D177E, G196E, T200A, L210F, L228R, A272P, T290TS | L295LR |
| >CA13883| codons 1-297 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYMDDLCVGSDLEIEQHRAKIEELRQHLFRWGFYTPDNKHQKEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALSEVIPRTE |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: Classification, amino acid mutation patterns, and prevalence in a northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |