<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
VL06_135 VL06_135 India 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14R, I15V, G16E, M36I, R41K, R57K, L63A, H69K, K70R, L89M, I93L  
>VL06_135| codons 1-99
PQITLWQRPLVTIRVEGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVKQYD
QIAIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39N, S48T, V60I, K101Q, K122E, I135R, S162H, P170S, K173T, Q174K, D177Q, E194G, G196E, T200A, Q207E, R211K, V245H, K263R, A272P, K281R, T286A, E291D, E297A  
>VL06_135| codons 1-300
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILESFRTKNPQIVI
YQYMDDLYVGSDLGIEQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIHLPEKDSWTVNDIQKLVGRLNWASQIYPGIKVKQLCRLLRGAKALTDVIPLTAEAE

References
Author Title Citation
Kandathil, AJ The frequency of HIV-I drug resistance mutations among treatment-naive individuals at a tertiary care centre in South India. Int J STD AIDS, 2009
Kandathil, AJ A comparison of interpretation by three different HIV type 1 genotypic drug resistance algorithms using sequences from non-clade B HIV type 1 strains. ARHR, 2009