Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Gat-NR7 | agaNR706 | Japan | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | IDV | 32 |
| 3 | RTV+SQV | 24 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, V82A, I84V, L90M | F53L | L10I, E34Q, N37D, K45N, L63P, A71V, V77I, I93L |
| >agaNR706| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLQEMDLPGRWKPNMIGGIGGLMKVRQYD QIPIEICGHKVIGTVLIGPTPANVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Gatanaga, H | Anti-HIV effect of saquinavir combined with ritonavir is limited by previous long-term therapy with protease inhibitors. | ARHR, 1999 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |
| Gonzales, MJ | Protease and reverse transcriptase mutation patterns in HIV-1 isolates from heavily treated persons: comparison of isolates from northern California with isolates from other regions. | ARHR, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |