<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT247 06TG.HT247 Togo 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T4P, Q7D, L10V, T12A, I13V, K14R, G16E, K20I, E35G, M36I, R41K, R57K, L63H, H69K, P79S, L89M  
>06TG.HT247| codons 1-99
PQIPLWDRPVVAVRIEGQLIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFIKVKQYD
QIHIEICGKKAIGTVLVGSTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215A     E6D, K20R, V35T, E36D, V60I, T69S, K122E, D123N, I135V, A158S, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, D250E, S251D, A272P, K277R, L283I, R284K, E291D, V292I, I293V, E297A, P321S, D324E, G335D, R356K, M357R, G359S, A371V, I375V, A376S, T377M, S379C, K390R, T403M, E432D, V435I, E449K  
>06TG.HT247| codons 1-449
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFRTNNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFATPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKEDWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIKGTKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDSSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKVSMECIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAANRK

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009