<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT170 06TG.HT170 Togo 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11I L10V, I13V, G16E, L19P, K20I, E35G, M36I, R41K, L63S, H69K, I72IV, V77I, L89M  
>06TG.HT170| codons 1-99
PQITLWQRPVITVKIEGQPIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFIKVRQYD
QISIEICGKKAVGTVLIGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, E36D, V60I, I135V, E138A, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, K277R, T286A, I293V, P294A, S322T, I326IV, Q334H, G335D, R356K, M357R, G359S, A371V, K390R, T403M, E432D, V435A  
>06TG.HT170| codons 1-444
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNATPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTRNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVVALTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGAETFYVDG

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009