<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT152 06TG.HT152 Togo 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35G, M36I, N37S, P39S, R41K, R57K, L63P, H69K, V77I, L89M  
>06TG.HT152| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEGISLSGKWKPKMIGGIGGFIKVKQYD
QIPIEICGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        T27S, V35T, T39N, E40D, E53D, K122E, D123E, K173T, Q174K, D177E, E203D, Q207E, R211K, V245Q, D250E, S251D, T286A, A288S, V292I, I293V, E297P, P345Q, F346H, M357E, R358K, G359S, E370G, A376T, T377M, S379C, K390R, K395R, A400T, E404D, V435I  
>06TG.HT152| codons 1-448
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICNDMEKEGKISKIGPDNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIDELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKEDWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKSLTEIVPLTPEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEQHKNLKTGKYAREKSA
HTNDVKQLTGAVQKITMECIVIWGKTPKFRLPIQRETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANR

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009