<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT139 06TG.HT139 Togo 2006 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G17E, K20I, E35D, M36I, R57K, L63S, C67M, H69K, K70R, V82I, L89M  
>06TG.HT139| codons 1-99
PQITLWQRPLVTVKIGEQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
QISIEIMGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35A, T39N, V60I, K122E, I142V, K173T, Q174K, D177E, I178M, T200A, Q207K, R211A, V245Q, E248D, D250E, S251D, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, V314I, Q334H, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, I375V, S379G, T386I, Q394R, E399D, A400V, V417I, K431T  
>06TG.HT139| codons 1-434
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALAEICNEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRKHLLAWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKEDWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGAKALTDIVPLTAEAE
MELAENREILKEPIHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEVVQKVATEGIVIWGKIPKFKLPIRKETWDVWWTEYWQATWIPEWEFINTP
PLVKLWYQLETEPI

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009