<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT085 06TG.HT085 Togo 2006 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16A, E35D, M36I, R41K, R57K, H69K, V77I, L89M  
>06TG.HT085| codons 1-99
PQITLWQRPVVTVKIAGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11T, T27S, V35T, T39K, K43E, K102KQ, D121H, K122E, D123S, I135T, I142V, S162Y, K173AV, Q174K, D177E, V179I, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294PT, E297EK, E312ED, I326V, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403M, W410H, E432D, V435I  
>06TG.HT085| codons 1-435
PISPIETVPVTLKPGMDGPKVKQWPLSEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL
HESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRVKNPEIII
YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTKEAE
LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVRQLVEVVQKVVTESIVIWGKTPKFKLPIQKETWETWWMEYWQATHIPEWEFVNTP
PLVKLWYQLEKDPII

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009