<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT058 06TG.HT058 Togo 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K32E, V35K, S68G, K122E, D123N, I135K, S162A, K173A, Q174K, D177E, I178IM, V179I, T200A, Q207E, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, K311R, E312N, G335D, P345PT, M357K, G359S, K366R, T369V, A371V, I375V, A376V, E399ED, A400T, T403M, W410Y, E432D  
>06TG.HT058| codons 1-434
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIEALKEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEMII
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTEEAE
LELAENREILRNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQETFKNLKTGKYARKRSA
HTNDVRQLVEVVQKVVTESIVIWGKTPKFKLPIQKETWDTWWMEYWQATYIPEWEFVNTP
PLVKLWYQLEKDPI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G16E, K20I, M36I, R41K, H69K, K70KE, L89X  
>06TG.HT058| codons 1-99
PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKEAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009