<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT050 06TG.HT050 Togo 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13A, K14R, L19S, K20I, A22V, E35D, M36I, R41K, L63H, H69K, K70R, L89I  
>06TG.HT050| codons 1-99
PQITLWQRPLVTARIGGQSIEVLLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIHIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36D, E40D, K122P, I135V, S162A, F171Y, K173T, Q174K, D177E, T200A, Q207N, V245T, K281R, T286A, E291D, I293V, L310I, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K390R, K395R, T403M, E404D, E432D  
>06TG.HT050| codons 1-433
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPYRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRNHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDVVPLTEEAE
LELAENREIIKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKVATEGIVIWGKTPKFRLPIQRETWEAWWMDYWQATWIPEWEFVNTP
PLVKLWYQLEKDP

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009