<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
HT046 06TG.HT046 Togo 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13AV, K14R, I15V, K20I, E35N, M36I, N37D, R41K, H69K, K70R, L89M  
>06TG.HT046| codons 1-99
PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLENIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215S     V35T, V60I, I135L, Q151X, S162A, K173A, Q174K, D177E, T200A, Q207E, V245M, K281R, T286A, E291D, V292VI, I293V, P294T, E297D, S322T, G335D, R356K, M357K, R358K, G359S, A371V, I375V, S379G, T386V, K390R, A400T, T403TM, E432D  
>06TG.HT046| codons 1-433
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPRGWKGSPAIFQASMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFSTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTDEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKKSA
HTNDVKQLTEVVQKVATEGIVIWGKVPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDP

References
Author Title Citation
Yaotse, DA Genetic characterization of HIV-1 strains in Togo reveals a high genetic complexity and genotypic drug-resistance mutations in ARV naive patients. Infect Genet Evol, 2009